The names we typically associate with scientific genius are from several centuries or millennia ago. Think Newton, Einstein, Archimedes, Galileo, or Darwin. Even famed scientists that are modern by comparison (Richard Feynman, Francis Crick, or Linus Pauling) made discoveries many decades ago. Just as any sports fan will tell you it is pointless to compare athletes from different eras, the same is true, if not more so, for scientists. Whereas athletes are largely playing the same game as they were decades ago, science has changed. We aim to always answer new questions, address ever more complex and interdisciplinary issues, and occasionally develop experiments costing billions of dollars. How, then, does scientific genius manifest in the 21st century? Which circumstances are most conducive to developing scientific genius? And what traits does a genius in the modern scientific realm exhibit?